Gap Junction Communication and Inflammation in Drug-induced Liver Injury

Suraj J. Patel, PhD, Massachusetts General Hospital

Suraj Patel, PhD, Research Fellow in Surgery, presented Clinical Grand Rounds on the topic of drug-induced liver injury at MGH GI Unit. The presentation was recorded 6 March 2012. [...]

Rational Use of Opioid Analgesics

James P. Rathmell, MD, Beth Israel Deaconess Medical Center, Massachusetts General Hospital

Dr James Rathmell, Vice Chair and Chief of the Division of Pain Medicine at Massachusetts General Hospital presented Clinical Grand Rounds at MGH GI Unit on the topic of opioid analgesics. The presentation was recorded 20 March 2012. [...]

Endoscopic submucosal dissection of a well-differentiated intestinal type intramucosal gastric adenocarcinoma

Sergio Coda, MD, PhD, Imperial College London, UK
Paolo Trentino, MD, University of Rome

This video demonstrates the ESD technique used to remove a type 0-IIa+IIc 15 mm early gastric cancer of the fundus in a 79 year-old male patient. The procedure took place in the operating theatre, under deep sedation, with back-up surgical team available. Preoperative endoscopy included contrast chromoscopy with 0.2% indigo carmine dye together w [...]

Cases from the Bigelow

Jay Luther, MD, Massachusetts General Hospital

Dr Jay Luther, GI Fellow at Massachusetts General Hospital presented clinical patient cases for Bigelow Rounds. The presentation was recorded 23 October 2012. [...]

Revitalizing the Dead Liver

Martin Hertl, M.D., Massachusetts General Hospital

Dr Martin Hertl, Surgical Director of the Liver Transplantation Program at Massachusetts General Hospital presents Clinical Grand Rounds at the MGH GI unit. The presentation was recorded September 4, 2012. [...]

Dilation, Stent Placement, and Electroincision of an Esophageal Stricture

Serag Dredar, MD, Yale University
Harry Aslanian, M.D., Yale University

A 67 yo male presented with dysphagia, 2 months after a distal esophagectomy for esophageal cancer. As shown here, the patient has a tight anastamotic stricture. Multiple staples can be seen adjacent to the stricture. A few of the staples were removed to allow for access to the esophageal lumen. A TTS dilation balloon catheter is just able to tr [...]

Complete Endoscopic Windsock Diverticulotomy Using a Duodenoscope

Sharlene L. D’Souza, MD, University of Michigan
Dejan Micic, MD, University of Michigan
B. Joseph Elmunzer, MD, University of Michigan

A 29-year-old female with no prior medical history was transferred to our facility for evaluation of post-prandial nausea and right upper quadrant abdominal pain. These symptoms had been present for the past three months. She reported emesis of undigested food within five minutes of oral intake, which resulted in the patient being on a liquid-onl [...]

Boerhaave’s syndrome

Jose Alberto Gonzalez-Gonzalez, MD, Centro Regional de Enfermedades Digestivas, UANL, Monterrey, Mexico
Jonas Villareal, MD, Centro Regional de Enfermedades Digestivas, UANL, Monterrey, Mexico
Hector J. Maldonado, MD, Centro Regional de Enfermedades Digestivas, UANL, Monterrey, Mexico

This is the case of 41 year old men with active chronic alcoholism how was admitted to the ER complain nausea and vomiting in multiples occasion during the pass two days. Two hours before to the admission, he started with sever abdominal pain and bright red blood hematemesis. Vital sign upon the arrival were blood pressure 90/60 HR: 110x. Laborat [...]

Cholangioscopic evaluation of a ‘dominant’ stricture in primary sclerosing cholangitis

Shyam Menon, MD, MRCP, University Hospital Aintree
Venkata Lekharaju, MRCP, University Hospital Aintree
Monica Terlizzo, MD, University Hospital Aintree
Richard Sturgess, MD, University Hospital Aintree

A 65-year old man with background primary sclerosing cholangitis (PSC) diagnosed 5 years previously presented with worsening jaundice, pruritus and weight loss. His liver function tests confirmed cholestatic jaundice. His Ca 19-9 levels were raised. Cross-sectional imaging with a CT suggested dilatation of the intrahepatic biliary system. A strictu [...]

Endoscopic gallbladder drainage and lavage using swing-tip catheter and a 20cm Johlin stent

Martin L. Freeman, M.D., University of Minnesota
Mustafa Tiewala, MD, University of Minnesota

In this video we will show gallbladder drainage in a 44 year old man with widely metastatic appendiceal carcinoma but good functional status, who had bilatereal nephrostomy tubes. He presented with RUQ pain, tenderness, normal LFTs, but CT and ultrasound showing a distended gallbladder with sludge, thus clear evidence of cholecystitis. He was felt [...]